April 11 - At New York's Yankee Stadium, the Minnesota Twins, in their first game since their move from Washington, shut out the Yankees 6-0. The Twins' Pedro Ramos was the winning pitcher. Ramos had a 2-run single and allowed just 3 singles in beating the Yankee starting pitcher, Whitey Ford.
April 22 - The Boston Red Sox snap a 13-game losing streak in Chicago's Comiskey Park by edging the Chicago White Sox 7-6 on Pumpsie Green's 11th inning home run.
April 27 - The Los Angeles Angles drew a disappointing crowd of 11,931 for their home opener against the Minnesota Twins at Los Angeles' Wrigley Field. Ty Cobb, in his last appearance at a ball park, throws out the first ball. The Twins' Camilo Pascual spoils the opener by winning, 4-2, sending the Angels to their 8th loss in 9 games.
May 31 - Boston Red Sox outfielder Carroll Hardy pinch-hits for rookie Carl Yastrzemski. On September 20, 1960, Hardy pinch hit for Ted Williams, making him the only player to go in for both future Hall of Famers. Hardy also hit his first major league home run pinch-hitting for Roger Maris when both were at Cleveland (May 18, 1958).
July 11 - Strong winds at Candlestick Park dominate the first All-Star Game of the season. A capacity crowd sees pitcher Stu Miller blown off the mound in the ninth inning when a balk is called, and it enables the American League to forge a 3–3 tie before losing 5–4 in 10 innings.
July 17 - Commissioner Ford Frick decrees that Babe Ruth's record of 60 home runs in a 154-game schedule in 1927 "cannot be broken unless some batter hits 61 or more within his club's first 154 games." Two days later, Frick, an old friend of Ruth, announces that should Ruth's record be beaten after 154 games, the record will carry an asterisk. When asked about the ruling, Roger Maris replies, "A season is a season."
July 31 - At Fenway Park, the second All-Star Game of the year ends in a 1–1 tie as heavy rain halted play. It is the first tie in All-Star history.
August 22 - Roger Maris becomes the first player to hit his 50th home run of the season in the month of August as the Yankees lose to the Los Angeles Angels 4-3. Angels' pitcher Ken McBride tees up the gopher ball in the 6th inning with one on.
Roger Maris hits his major league record-tying 60th home run of the season, a 3rd inning solo shot against Jack Fisher of the Baltimore Orioles.
October 1 - Before a small crowd at Yankee Stadium, New York Yankee Roger Maris smacks a 2-0 pitch into right field for his 61st home run of the season (a record that would last until Mark McGwire broke it in 1998).
October 9 - In Game Five of the World Series, Johnny Blanchard and Héctor López spark a five-run first inning and 13–5 win for the New York Yankees over the Cincinnati Reds. Blanchard and López hit home runs, and López drives in five runs. Bud Daley's long relief effort wraps up the Series, as Ralph Houk becomes the third rookie manager to guide a World Series winner. Whitey Ford is named the Series MVP.
January 5 - Fred Luderus, 75, Phillies first baseman of the 1910s, captain of the 1915 NL champions
January 8 - Schoolboy Rowe, 50, 3-time All-Star pitcher who won 158 games, mainly with the Tigers and Phillies (1st to appear in All-star Game for both leagues).
January 30 - Aaron Ward, 64, second baseman on the Yankees' first World Championship team in 1923
February 16 - Dazzy Vance, 69, Hall of Fame pitcher who led the NL in strikeouts seven years in a row and won the 1924 MVP award
April 23 - Jack Barry, 73, shortstop in the Athletics' "$100,000 infield", coach since 1921 at Holy Cross, where he won the 1952 College World Series and posted the highest career winning percentage (.806) in collegiate history
April 28 - Tommy Connolly, 90, Hall of Fame umpire from 1898 to 1931 who worked the first American League game ever, as well as the first contests at Comiskey Park, Shibe Park, Fenway Park, and Yankee Stadium
June 18 - Eddie Gaedel, 36, 3'7" player who made one appearance for the 1951 Browns in a stunt promotion
July 17 - Ty Cobb, 74, Hall of Fame center fielder widely recognized during his lifetime as one of the greatest players in the sport's history, and holder of more records than any other player including highest lifetime batting average (.366) and most career hits (4,189), runs (2,246), steals (892), games (3,034) and at bats (11,434). Cobb is credited with 11 batting titles.
July 17 - Ed Reulbach, 78, pitcher who starred for the Cubs from 1905 to 1913, winning 182 career games
July 18 - Hod Eller, 67, pitcher for the Reds from 1917-1921, including a 1919 World Series game which saw him strike out 6 in a row
August 3 - Thomas Edward Downey, 77, played from 1909 to 1915 for the Reds, Phillies, Cubs, and Bisons.
September 9 - Jesse Barnes, 69, pitcher who won 152 games for the Braves, Giants and Dodgers, including a no-hitter
September 9 - Rube Oldring, 77, outfielder who played mainly for the Athletics, including 4 pennant winners
December 15 - Dummy Hoy, 99, center fielder who scored over 100 runs nine times, and the game's most accomplished deaf player; he threw out the first ball of the World Series' third game on October 7
