Versatile and valuable anywhere he plays, Wilson has had a rather eventful career, mostly as a backup at second base, third and shortstop, playing hitters well, and has a strong arm. Wilson has some pop in his bat, and he will run occasionally, but he is smart enough not to try to steal very often.
Had the Yankees won Game 7 of the 2001 World Series, Wilson would have departed to the Dominican Republic on the deadly American Airlines Flight 587 . Yankees closer Mariano Rivera says that he is happy that he blew the save in game 7 because that way he still has a friend (Wilson).
In 2003, Enrique Wilson was involved in an incident where Manny Ramírez missed a game claiming to have a sore throat, but was later found to actually have been partying in a hotel room with Wilson. At the time, Wilson played for the rival New York Yankees.
Wilson had surprisingly very good numbers off of pitcher Pedro Martínez, one of the better pitchers in the game.
In 2006, Wilson played for the Boston Red Sox's Triple A team the Pawtucket Red Sox and retired in August.